Recombinant mouse IGF-2/IGF-II protein (His tag)

Size: 100μg

Catalogue Numbers: PDEM100107-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: IGF-2; IGF-II

Target Synonym: Insulin-like growth factor II; Igf2; IGF-II; Multiplication-stimulating polypeptide

UNIProt ID: P09535

Research Areas: Cancer; Developmental Biology; signal Transduction; Stem Cells

Target Species: Mouse

Expression Host: E.coli

Fusion Tag: N-His

Accession: P09535

Background: Insulin-like growth factor I (also known as somatomedin C and somatomedin A) and insulin-like growth factor II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved (100% identity between human, bovine and porcine proteins) and exhibit cross-species activity.
IGF-II is a potent mitogenic growth factor. However, unlike IGF-I which has important postnatal roles, the growth-promoting function of IGF-II is limited to embryonic development.

Sequence: Ala 25-Leu 126

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 11.11 kDa

Observed MW: 14 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only