Recombinant Mouse TNF-α protein (His tag)

Size: 100μg

Catalogue Numbers: PDEM100067-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: TNF-α

Target Synonym: Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Tnf; Tnfsf2; DIF; TNF-alpha; Tnfa; TNFalpha; Tnfsf1a; TNFSF2

UNIProt ID: P06804

Research Areas: Cancer; Cardiovascular; Metabolism Immunology; Signal transduction

Target Species: Mouse

Expression Host: E.coli

Fusion Tag: N-His

Accession: P06804

Background: Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.

Sequence: Leu 80–Leu 235

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 17.05 kDa

Observed MW: 17 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only