Recombinant Human NHP2/NOLA2 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032829-10, PKSH032829-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: NHP2; NOLA2

Target Synonym: H/ACA ribonucleoprotein complex subunit 2; Nucleolar protein family A member 2; snoRNP protein NHP2; NHP2; NOLA2; NHP2P.

UNIProt ID: Q9NX24

Research Areas: epigenetics and nuclear signal

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-6His

Accession: Q9NX24

Background: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Sequence: Met 1-Leu153

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 100mM NaCl, 1mM DTT, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 19.3 kDa

Observed MW: 22 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only