Recombinant Human PSPH Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032897-10, PKSH032897-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: PSPH

Target Synonym: Phosphoserine Phosphatase; PSP; PSPase; L-3-Phosphoserine Phosphatase; O-Phosphoserine Phosphohydrolase; PSPH

UNIProt ID: P78330

Research Areas: Signal Transduction; metabolism;

Target Species: Human

Expression Host: E.coli

Fusion Tag: C-6His

Accession: P78330

Background: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation; moderate psychomotor retardation and facial features suggestive of Williams syndrome.

Sequence: Met 1-Glu225

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 250mM NaCl, 50mM Imidazole, pH 8.5 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 26.1 kDa

Observed MW: 29 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only